mibi uptake in a huge breast mass obscuring the anterior and lateral myocardial walls in perfusion imaging

background: cardiac risk assessment with myocardial perfusion imaging (mpi) is a common practice for some elderly breast cancer patients who are candidates for operation. in rare cases the tumor may become visible in the images. case presentation: this is the report of a case with a huge slow-growing breast tumor suspicious for malignancy and presenting with methoxy-isobutyl-isonitrile (mibi) uptake in the tumor. the patient was referred to the nuclear medicine department for preoperative cardiac risk assessment with mpi. conclusion: there was high uptake in the tumor was note worthy in two different aspects: 1)high mibi uptake in the tumor is more suggestive of malignant rather than benign tumors and thus, underscores the importance of extra-cardiac uptake sites in pre-operation mpi; and 2)high uptake in the left breast tumor may obscure the mpi image and hinder proper interpretation.